Kate Rheinstein Brodsky has her mother’s eyes. Her eyes for design, that is. The daughter of legendary decorator Suzanne Rheinstein, she grew up traveling, collecting, and helping out at Hollyhock, Rheinstein’s much-celebrated Los Angeles shop. It seems only appropriate, then, that Brodsky should set up her own delightful boutique in New York City, where she has lived since she was a student at NYU.

KRB, which uses Brodsky’s swirling initials as its logo, opened last month on Manhattan’s Upper East Side, tucked into a cozy space not far from the apartment she shares with her young family. A fresh take on traditional, the store mixes antiques of every era—a grouping of 19th-century Japanese lacquer tray tables, an exuberant 18th-century rococo mirror, a neoclassical Italian commode—with contemporary pieces from the Lacquer Company and design-minded cocktail table books. Monochromatic waxlike encaustic paintings from New York–based artist LeRone Wilson hang alongside 19th-century engravings, and Brodsky’s contemporary furniture designs, such as a stainless-steel-and-wood table, bring things into the present day. She plans to add more of her own furnishings, inspired by the 20th-century designs of Jansen and Jean-Michel Frank. The interior, a jewel box down to its rich color scheme, pulls the different periods together with one of Brodsky’s favorite colors—a deep chartreuse—seen on the shelving, the molding, and one bold accent wall. “My mother taught me that there’s a lot of potential in everything,” Brodsky says. “I’m intrigued by it all.”

KRB, 135½ East 79th Street, New York; krbnyc.com